Effect of N-nitrosodiethylamine on the carcinogen-activating and -detoxifying enzymes in guinea pigs given excessive doses of ascorbic acid.

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THE EFFECT OF ASCORBIC ACID ON BLOOD HISTAMINE LEVEL AND DELAYED-TYPE HYPERSENSITIVITY IN GUINEA PIGS

The effect of ascorbic acid on blood histamine level and delayed-type hypersensitivity was studied in thirty male guinea pigs. Animals were sensitized to B.C.G., trichophytin and mallein during the first four weeks. The diet was ad libitum during this period. After this "sensitization period" animals w er e tested intradermally with tuberculin, trichophytin and mallein. The number and diam...

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15 صفحه اول

Effect of graded doses of erythorbic acid on ascorbic acid content of tissues of guinea pigs.

The effect of graded doses of erythorbic acid (ErA) on the content of ascorbic acid (AsA) in the tissues of guinea pigs administered AsA was studied. The guinea pigs were administered 5 mg AsA and 1, 5, 20, and 100 mg ErA; or 1 mg AsA and 1 and 20 mg ErA; or 20 mg AsA and 20 mg ErA for 16 days. The animals were then sacrificed, and the liver, adrenal glands, spleen, and kidneys were removed to ...

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ژورنال

عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition

سال: 1990

ISSN: 1880-5086,0912-0009

DOI: 10.3164/jcbn.8.201